Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been formally diagnosed with Major Depressive Disorder (MDD) as their main condition, confirmed by a qualified psychiatrist using standard diagnostic guidelines (DSM-5).
- People who also experience anxiety or anxiety symptoms alongside their depression, as long as depression remains the primary diagnosis.
- People whose depression is rated as at least moderately severe, based on a specific depression rating scale called the MADRS (a score of 20 or above is required).
- People who have been taking the same psychiatric medication(s) at a stable dose for at least 6 weeks before the study begins.
Who may not be able to join:
- People who have been diagnosed with another serious psychiatric condition in addition to MDD.
- People who have significant physical health conditions that could affect their ability to participate or make the study results harder to interpret.
- People who are currently receiving a structured form of talking therapy or any other treatment outside of their standard psychiatric medication.
- People who are experiencing active thoughts of suicide at the time of screening, as assessed using a specific clinical scale (C-SSRS).
- People who are currently misusing or are dependent on alcohol or drugs (excluding nicotine).
- People with an intellectual disability, or any condition that would make it difficult to give informed consent or complete the study — for example, severe vision or hearing impairment.
- People who are pregnant.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +34 937231010
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in depressive symptom severity, as measured by the Montgomery-Åsberg Depression Rating Scale (MADRS), from baseline to post-intervention.; Change in depressive symptoms measured by the Hamilton Depression Rating Scale (HAM-D), from baseline to post-treatment; Change in self-reported anxiety symptoms measured by the Beck Anxiety Inventory (BAI), from baseline to post-intervention; Change in self-reported depressive symptoms measured by the Beck Depression Inventory-II (BDI-II), from baseline to post-intervention; Change in salivary cortisol levels (Cortisol Awakening Response and Diurnal...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.