Colorectal Cancer Trial, Recruiting NCT07056374 Sponsor: Amsterdam UMC, location VUmc Condition: Colorectal Cancer
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Colorectal Cancer Trial, Recruiting

NCT07056374
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a biopsy-confirmed cancer of the sigmoid colon or upper rectum (at a specific early-to-moderate stage, without spread to distant parts of the body), where a surgical procedure called an anterior resection is the recommended treatment.
  • People who have a pre-cancerous growth in the sigmoid colon or upper rectum that cannot be removed by endoscopy, where an anterior resection is the recommended treatment.
  • People whose condition is suitable for a curative (aimed at curing) anterior resection surgery.
  • People whose condition is suitable for planned (non-emergency) keyhole surgery, either laparoscopic or robotic.
  • People who are mentally able to understand the study information, give informed consent, and complete questionnaires.

Who may not be able to join:

  • People who have an existing health condition requiring emergency surgery, such as a blocked or perforated bowel, infection inside or outside the bowel, or reduced blood supply to the intestine.
  • People whose cancer has spread to distant parts of the body (Stage IV cancer).
  • People who have a narrowing or blockage in the bowel or anal area below where the surgical join would be made.
  • People who have previously had radiation therapy to the pelvis, including combined chemotherapy and radiation given before surgery.
  • People for whom general anaesthetic is not considered safe.
  • People for whom a temporary ileostomy (a bag attached to an opening in the abdomen) is planned as part of their treatment.
  • People who are unable to receive bowel preparation (a cleansing process before surgery) or at least two enemas before the operation.
  • People whose immune system is weakened, for example because they are taking steroid medications or receiving immunotherapy.
  • People with any condition that, in the opinion of the research team, could interfere with the study — in particular, conditions that may cause significant thickening of the bowel wall, such as a history of repeated diverticulitis (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +31 (0)20 566 2714

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Amsterdam UMC, location VUmc
Registry
ClinicalTrials.gov
Start date
25 March 2025
Est. completion
1 October 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Anastomotic leakage rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov