Phase 3 Gastro-oesophageal Reflux Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older
- People who still have ongoing heartburn and/or regurgitation symptoms despite taking a standard acid-reducing medication (called a PPI) for at least 8 weeks
Who may not be able to join:
- People whose heartburn or reflux symptoms come with warning signs such as difficulty swallowing, unexplained weight loss, bleeding, vomiting, or anaemia
- People whose GERD symptom questionnaire score is below 8 (this is a standard scoring tool used by the trial team)
- People found to have a stomach or small intestine ulcer on a camera examination (endoscopy)
- People with other conditions affecting the food pipe (oesophagus), such as achalasia, cancer of the oesophagus, or scarring from a corrosive injury
- People with any cancer affecting the digestive system
- People who have had major surgery on the digestive system in the past
- People with a medical condition that affects how the food pipe or stomach moves, such as poorly controlled diabetes, or an overactive or underactive thyroid
- People with reduced kidney function
- Women who are pregnant or breastfeeding
- People currently taking medications that affect a specific muscle at the base of the food pipe (confirm with trial site for specific drug names)
- People who regularly take medications that may interact with Baclofen (the study drug) — the trial site can advise on which medications are relevant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +8801311286376
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Improvement of GERD symptoms
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.