Peripheral Neuropathy Trial, Recruiting NCT07064798 Sponsor: Dana-Farber Cancer Institute Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT07064798
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have been diagnosed with a gynecologic cancer (such as ovarian, cervical, or uterine cancer) or breast cancer
  • You are about to start your first cycle of certain chemotherapy treatment plans involving paclitaxel, with or without other chemotherapy drugs (confirm specific regimen details with trial site)
  • You are receiving your cancer treatment at the main Dana-Farber Cancer Institute (DFCI) campus locations (currently Yawkey 9 and 10, or Chestnut Hill)
  • You are able to fill out questionnaires written in English or Spanish

Who may not be able to join:

  • You have previously received chemotherapy that is known to cause nerve damage
  • You already have nerve damage or a nerve condition (such as numbness or tingling) before starting this trial
  • You have a history of certain blood or circulation conditions, including Raynaud's phenomenon, cold agglutinin disease, cryoglobulinemia, cryofibrinogenemia, post-traumatic cold dystrophy, peripheral arterial ischemia, or sickle cell disease (confirm with trial site)
  • You are currently going through a desensitization treatment process (confirm with trial site)
  • You have lymphedema (swelling caused by fluid buildup) in the arm or leg where the trial device would be placed
  • You have open skin wounds or sores on the arms or legs where the trial device would be placed

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Theresa Jabaley Leonarczyk, PhD, RN, Dana-Farber Cancer Institute

Phone: 617-582-8037

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
22 October 2025
Est. completion
1 August 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Patient-Reported CIPN Symptoms Assessed by the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy module at End of Treatment; Duration of Cryocompression Tolerated During Neurotoxic Chemotherapy; Incidence of Core Temperature Decrease >1°F and Skin Intolerance Symptoms Associated with Cryocompression

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov