Phase 2 Depression and Anxiety Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a man or woman between 18 and 65 years old (inclusive) and are able to understand and sign a consent form.
• You have been formally diagnosed with major depressive disorder (MDD) as your main condition; you may also have certain anxiety conditions (such as generalized anxiety, social anxiety, or panic disorder) as long as depression is considered the main focus of your care.
• You are currently in a depressive episode that has lasted at least 4 weeks but no longer than 18 months before the screening visit.
• If you are a woman who could become pregnant, you must agree not to become pregnant during the study or for 30 days after your last dose, must not be breastfeeding, and must use a highly effective form of contraception throughout.
• Your body mass index (BMI) — a measure of body weight relative to height — falls between 18 and 40.
• You are willing and able to avoid using recreational or illegal drugs during the study.

Who may not be able to join:

• You have a history of, or currently show signs of, depression with psychotic or catatonic features (confirm with trial site).
• You have ever had a manic, hypomanic, or mixed episode, including episodes triggered by antidepressants.
• You have a diagnosis of bipolar disorder, including bipolar depression.
• You have a diagnosis of schizophrenia, schizoaffective disorder, or another psychotic disorder.
• You have obsessive-compulsive disorder (OCD).
• You have any lasting condition affecting memory, thinking, or cognition (confirm with trial site).
• Your current depressive episode has already involved two or more antidepressant treatments that did not work at the right dose and for the right length of time (sometimes called treatment-resistant depression).
• You have been admitted to a psychiatric hospital during your current depressive episode.
• You have a significant medical condition or history that could affect your ability to participate safely (confirm with trial site).
• You have previously had a bad reaction, intolerance, or allergy to the study drug or any of its ingredients.
• You have a history of alcohol or drug use disorder.
• You test positive for cannabis (marijuana) at screening.
• You are considered to have a significant risk of suicide or of harming yourself or others.

Important: Always verify eligibility with the trial site directly before applying.