Depression and Anxiety Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 65 years old
• You are able to give your consent to participate in the study
• You can read and communicate in English
• You have scored above 10 on a standard depression questionnaire (PHQ-9), meaning you have at least moderate symptoms of depression
• You have completed a required waiver form for the community partners involved in the study before enrolling
• If you could become pregnant, you are willing to use an acceptable form of birth control during the study
• If you are already taking psychiatric medications or attending therapy, you are willing to keep these the same throughout the study
• You have access to a smartphone, iPad, or similar device that can run a mindfulness app
• You are able to travel to a location called "Breathe" in Harvard Square, and to at least one "Restore" location (in Hingham, Somerville, Dedham, Newton, or Lynnfield)

Who may not be able to join:

• You are currently pregnant or planning to become pregnant during the study
• You are currently breastfeeding
• You are currently having thoughts of suicide (as identified through standard screening tools used by the study team)
• You have had an active eating disorder or substance use disorder within the past 12 months (as assessed by a standard screening interview)
• Your primary mental health condition is OCD (Obsessive-Compulsive Disorder) or PTSD (Post-Traumatic Stress Disorder), as identified by a standard screening interview
• You have a history of bipolar disorder or psychotic disorders, as identified by a standard screening interview
• Your depression score dropped by 25% or more between your first screening and the start of the study
• You are currently under the influence of, or going through withdrawal from, drugs or alcohol
• A urine drug test shows the presence of illegal drugs or other medications that disqualify you from the study (unclear cases will be reviewed individually by the study lead)
• You have had a bone fracture or joint surgery in the past 6 months
• You have difficulty walking or cannot walk freely
• You have a serious or unstable health condition identified through a standard physical activity health questionnaire (PAR-Q+), unless your own doctor has approved your participation
• You do not have a healthcare provider you could contact if needed — such as a primary care doctor, counselor, psychiatrist, nurse practitioner, or regular clinic
• You have attended more than 6 heated yoga classes in the past 3 months
• You have used a sauna more than 6 times in the past 3 months
• You have used a mindfulness app more than 6 times in the past 3 months
• You take certain medications that increase the risk of dehydration or have certain health devices — for example, lithium, antipsychotics, insulin, diuretics, barbiturates, beta-blockers, anticholinergics, or if you have a pacemaker or hemophilia (confirm with trial site)
• You started an antidepressant or psychiatric medication less than 8 weeks ago, or had a dose change less than 4 weeks ago
• You started a new course of therapy (psychotherapy) within the past 3 months
• You have been admitted to a psychiatric hospital within the past year
• You have a neurological condition that could affect your ability to participate safely
• You are currently receiving ketamine treatment, electroconvulsive therapy (ECT), or transcranial magnetic stimulation (TMS)
• You are unable to follow the study procedures, such as travelling to the heated yoga or sauna locations
• The study's Principal Investigator has determined that your participation would not be safe or could affect the quality of the study

Important: Always verify eligibility with the trial site directly before applying.