Gastro-oesophageal Reflux Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are willing to take part and have signed a written consent form
- People whose blood sugar levels are stable and well-controlled
- People whose diabetes treatment (such as metformin, certain tablets, or insulin) has not changed — including no new medications added — in the 6 months before joining
- People whose diabetes medication doses have remained the same for at least 6 months before joining
- People who agree not to start any new medications during the study
Who may not be able to join:
- People who are pregnant or breastfeeding
- People with liver cirrhosis, as confirmed by liver biopsy, a liver stiffness scan result of 14 kPa or higher, or certain liver blood test scores above set thresholds
- People who have frequent watery diarrhoea (more than 3 loose stools per day)
- People with chronic heart failure, at any stage of severity
- People who have had major surgery on the abdomen or chest in the past, including weight-loss surgery or reflux surgery (though appendix or gallbladder removal more than one year before joining may be acceptable — confirm with trial site)
- People with certain swallowing disorders affecting the oesophagus or the junction between the oesophagus and stomach (confirm with trial site)
- People with major oesophageal movement disorders as classified under a specific medical classification system (confirm with trial site)
- People who have had a serious heart or cardiovascular event in the 6 months before the screening visit
- People with high blood pressure that remains uncontrolled despite treatment
- People with Type 1 diabetes
- People whose HbA1c (a measure of long-term blood sugar control) is above 9.0%
- People with a known allergy or sensitivity to the study product or any of its ingredients, including lactose intolerance
- People currently taking certain medications known to affect how the oesophagus moves, such as some blood pressure medications, muscle relaxants, antidepressants, or similar drugs
- People with any condition that may significantly affect life expectancy, including known cancers
- People with significant immune, hormonal, blood, digestive, neurological, tumour, or psychiatric conditions
- People whose mental health or capacity may affect their ability to consent, take part, or follow the study requirements
- People who are unable to tolerate a specific oesophageal test procedure (high-resolution manometry) without sedation
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Sergey Morozov, MD, PhD, Federal Research Center of Nutrition and Biotechnology
Phone: 4996131091
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Mean lower esophageal sphincter resting pressure; Distal contractile integral; mean lower esophageal sphincter integral relaxation pressure; Mean contractile front velocity; Distal latency; Mean intrabolus pressure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.