Mesothelioma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must have a confirmed diagnosis of a specific type of mesothelioma (called "epithelioid" subtype) affecting the lining of the lung, confirmed through a surgical biopsy procedure.
• The cancer must be located only on one side of the chest.
• Your cancer must be considered either unable to be fully removed by surgery, or only possibly removable with complex surgery, based on CT or MRI scans showing it has grown into nearby structures or is very large.
• You must have already completed at least 6 weeks of chemotherapy or immunotherapy treatment (such as certain drug combinations including platinum-based chemotherapy, pemetrexed, pembrolizumab, bevacizumab, or ipilimumab/nivolumab), with no serious unresolved side effects.
• You must be 18 years old or older.
• You must be generally healthy and active enough to carry out daily activities with no more than minor limitations (confirm with trial site).
• Your blood, liver, and kidney test results must be within acceptable ranges as measured by specific blood tests.
• If you have HIV, you must be on effective treatment with an undetectable level of the virus in the past 6 months.
• If you have a history of hepatitis B, the virus must be at undetectable levels while on treatment.
• If you have a history of hepatitis C, you must have been successfully treated and cured, or currently on treatment with undetectable virus levels.
• If you have a history of heart disease or have received treatments that can affect the heart, your heart function must meet a minimum standard as assessed by your doctor (confirm with trial site).
• Your case must have been reviewed by a team of specialists including surgeons, radiologists, pathologists, cancer doctors, and palliative care doctors.
• You must be enrolled or willing to enroll in a related tissue research study at the University of Chicago.
• You must be willing and able to sign an informed consent form agreeing to take part in the trial.

Who may not be able to join:

• People who have a different subtype of mesothelioma (called "biphasic" or "sarcomatoid") cannot join.
• People whose cancer has spread to other parts of the body, or into the abdominal (belly) area, cannot join.
• People whose cancer continued to grow or spread during or after their initial treatment cannot join.
• People whose lung function test results fall below certain thresholds, suggesting the lungs are not strong enough for surgery, cannot join (confirm with trial site).
• People who are currently participating in another clinical trial involving an experimental treatment cannot join.
• People who have another illness that is not well controlled cannot join.
• People who have had another type of cancer that was active within the past 2 years cannot join, unless it was an easily treatable skin cancer, early-stage bladder cancer, or a very early-stage cancer of the prostate, cervix, breast, or thyroid that has been successfully treated.

Important: Always verify eligibility with the trial site directly before applying.