Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 14 to 19 years old
- People who have been diagnosed with major depressive disorder, or bipolar I or II disorder, currently in a depressive episode without psychotic or mixed features
- People whose current depressive episode has lasted at least 4 weeks
- People who have tried at least one talking therapy or antidepressant medication that did not work well enough
- People whose depression scores as moderate to severe on a standard rating scale used by clinicians (the GRID-HAMD-17)
- People who are currently admitted to a hospital, or for whom a planned hospital admission would be appropriate
Who may not be able to join:
- People who have ever been diagnosed with a psychotic disorder, anorexia nervosa, or bulimia nervosa, or who have been diagnosed with a substance use disorder (other than caffeine or tobacco) in the past year
- People whose main source of distress is obsessive compulsive disorder or a personality disorder
- People currently experiencing psychosis or a manic episode
- People with a history of epilepsy or any other neurological condition that has involved seizures
- People taking medications that are known to lower the threshold for seizures (confirm with trial site)
- People who are pregnant or breastfeeding
- People who have experienced severe headaches within the past year
- People whose depression symptoms have improved by 25% or more between the initial screening appointment and the start of the trial
- People who would not be able to follow the trial's required procedures
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
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Trial details
Where this trial is recruiting
Primary endpoints
Feasible: 90% of the time, rTMS treatment will be started within 3 business days of a patient consenting during an existing inpatient stay or within 3 business days of the start of an elective inpatient stay; Feasible: 90% completion of weekly Hamilton Depression Rating Scale during treatment by clinician; Acceptable: 25% or lower drop-out rate from completing treatment; Accessible: 90% of the time, suitability assessments for this treatment pathway will be completed within 2 business days for exiting inpatients and within 2 weeks for outpatients; Demand: at least 30 youth will consent to bein...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.