Phase 1 Parkinson's Disease Trial, Recruiting NCT07157345 Sponsor: Ruijin Hospital Condition: Parkinson's Disease
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Phase 1 Parkinson's Disease Trial, Recruiting

NCT07157345
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been formally diagnosed with primary Parkinson's disease, confirmed using recognised international or Chinese diagnostic guidelines
  • People aged between 40 and 65 years old (inclusive) at the time of screening, of any sex
  • People whose Parkinson's disease was diagnosed 5 years ago or less
  • People whose Parkinson's symptoms, when not on medication, are at a mild stage (Hoehn & Yahr stage 2 or below)

Who may not be able to join:

  • People whose condition has been identified as an atypical or secondary form of parkinsonism, such as a Parkinson's-plus syndrome, a hereditary form, or parkinsonism caused by medication
  • People who have a medical reason why surgery would not be safe for them, or who have previously had a brain procedure such as deep brain stimulation, pallidotomy, or similar surgery
  • People whose prior brain scans have shown structural abnormalities, blood vessel problems, brain tumours, bleeding risk, brain injury, or other significant findings
  • People who score below 24 on a standard memory and thinking assessment (confirm with trial site)
  • People who score 16 or above on a standard depression screening questionnaire (confirm with trial site)
  • People whose liver or kidney function test results are significantly above the normal range
  • People who have a blood clotting disorder or who are currently taking blood-thinning medication
  • People who test positive for Hepatitis B, Hepatitis C, HIV, or syphilis during screening
  • People who are currently receiving antiviral treatment for Hepatitis B or C

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 64370045

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Registry
ClinicalTrials.gov
Start date
20 October 2025
Est. completion
31 January 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

PDR-001 treatment-related adverse events as assessed by CTCAE v5.0; Titer levels of capsid neutralizing antibodies and binding antibodies against recombinant adeno-associated virus (rAAV) in serum; Titer of rAAV vectors in whole blood

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov