Printed from Voxsanity (voxsanity.com.au) — NCT07172412 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Phase 2 Lung Cancer Trial, Not Yet Recruiting
NCT07172412
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- A confirmed diagnosis of small cell lung cancer (SCLC) based on tissue or cell testing, with imaging showing the cancer has spread widely (classified as "extensive stage").
- People who have not yet received any systemic treatment for advanced or metastatic SCLC, or people whose cancer returned after combined chemotherapy and radiation treatment given at an earlier, localised stage.
- A life expectancy of at least 12 weeks.
- At least one area of cancer that can be measured on scans and has not previously been treated with radiation therapy.
- A general health and activity level rated as 0 or 1 on a standard medical scale (meaning fully active or able to carry out light activity).
- Blood counts within acceptable ranges at the time of screening, without having needed a blood transfusion or blood-stimulating medication in the 10 days before testing (confirm with trial site for specific numbers).
- Liver, kidney, and blood-clotting function within acceptable ranges at the time of screening (confirm with trial site for specific values).
- Women who could become pregnant must have a negative pregnancy test at screening, and all participants who could father or bear a child must agree to use effective contraception throughout the study and for at least one year after treatment ends.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have brain or central nervous system (CNS) metastases that are causing symptoms at the time of screening (those with no symptoms, or whose CNS metastases have been treated and have been stable for at least 4 weeks, may still be considered).
- People with a history of certain brain or nervous system conditions before screening, such as epilepsy, stroke, paralysis, dementia, Parkinson's disease, or autoimmune diseases affecting the central nervous system.
- People who received chemotherapy, radiation, immunotherapy, targeted therapy, biological therapy, or hormone-based cancer treatment within 4 weeks of screening, and who the trial doctor has assessed as not suitable for enrolment.
- People whose side effects from previous cancer treatments have not improved to a mild level (as defined by a standard medical grading system), with some exceptions such as hair loss or mild nerve-related side effects.
- People who have been taking systemic steroid (hormone) medications and stopped less than 72 hours before the first dose, although low-dose replacement hormone therapy may be permitted (confirm with trial site).
- People who have previously received an organ or tissue transplant.
- People known to have an active autoimmune disease affecting the whole body and who are currently receiving treatment for it.
- People who test positive for certain infections at screening, including active hepatitis B, hepatitis C, syphilis, HIV, or certain viral infections detected through DNA testing (confirm with trial site for specific thresholds).
- People who had major surgery or a serious physical injury within 4 weeks before screening, or who are expected to need planned surgery during the trial, and who the trial doctor has assessed as unsuitable for enrolment.
- People who have had another type of cancer within the past 2 years, or who currently have another cancer.
- People with certain heart conditions at screening, including significant heart failure, poorly controlled high blood pressure or pulmonary high blood pressure, a recent serious heart or stroke event within 6 months, significant heart valve disease, or serious heart rhythm or conduction problems (confirm with trial site for full details).
- People whose cancer involves the heart chambers (atrium or ventricle) at screening.
- People who have a medical emergency caused by the tumour blocking or compressing something, such as a bowel blockage or blood vessel compression, at the time of screening.
- People who have active bleeding at the time of screening.
- People who have had a blood clot in a deep vein or in the lungs within the 6 months before screening.
- People who have received a live vaccine within 6 weeks before screening.
- People with a bacterial, viral, or fungal infection that cannot be controlled even with appropriate treatment.
- People who have participated in another interventional clinical trial within 4 weeks before the first dose.
- People who are unlikely to follow the trial requirements, or who the trial doctor considers unsuitable for other reasons.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Contact this trial
Phone: +86-22-23340123-3210
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
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Trial details
Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 November 2025
Est. completion
1 December 2027
Where this trial is recruiting
🇨🇳 China
Primary endpoints
PFS; ORR; OS
Can't join this trial?
Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.