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Phase 2 Lung Cancer Trial, Not Yet Recruiting
NCT07177105
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults between 18 and 75 years of age (any sex).
- People with a laboratory-confirmed diagnosis of advanced (stage III or IV) non-squamous non-small cell lung cancer (a specific type of lung cancer) that cannot be surgically removed, as determined by a specialist medical team.
- People whose lung cancer tests negative for two specific genetic changes known as EGFR mutation and ALK rearrangement.
- People whose lung cancer shows no signs of being, or having changed into, a type called small cell lung cancer.
- People who have not yet received any cancer treatment.
- People who are generally well enough to carry out daily activities, as measured by a standard medical scoring tool (a score of 0 or 1 on the ECOG scale).
- People whose life expectancy is estimated to be at least 6 months.
- People whose main tumour measures at least 1 cm across and who have at least one measurable area of cancer remaining after any previous surgery, assessed using standard measurement guidelines.
- People whose blood counts meet minimum levels: enough neutrophils (a type of white blood cell), platelets, and haemoglobin (confirm specific values with trial site).
- People whose liver function test results are within acceptable ranges, with slightly higher limits allowed if liver spread is present (confirm specific values with trial site).
- People whose kidney function results are within acceptable ranges, based on either a blood test or a calculated kidney function score (confirm specific values with trial site).
- People whose lung function meets at least one of the following: a breathing test result (FEV1) of at least 1.2 litres or 40% of the expected value; a ratio of two breathing measurements (FEV1/FVC) of at least 0.7; a carbon monoxide diffusion test result of at least 40% of the expected value; or, if breathing results fall below these levels, additional lung function tests such as a perfusion scan or exercise test may be used to assess suitability (confirm with trial site).
- People who have been assessed by the study medical team and confirmed to be well enough to undergo surgery to remove the main tumour.
- People who are willing to follow the study plan and have given written consent to participate.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People with a history of a primary immune system disorder, or who have previously received an organ transplant or a stem cell transplant from another person.
- People with active cancer spread to the brain; however, people whose brain metastases have been adequately treated and whose condition has been neurologically stable for at least two weeks before joining may be considered, provided they are not taking corticosteroids or are on a low and stable or reducing dose (confirm with trial site).
- People who are pregnant.
- People with a serious, uncontrolled, or unstable health condition that the investigating doctor believes could interfere with participation or affect the study results, including uncontrolled seizures, psychiatric disorders, active or uncontrolled infections, or other significant conditions or abnormal test results.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
GP referral letter
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Trial details
Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Jianxing He
Registry
ClinicalTrials.gov
Start date
10 September 2025
Est. completion
1 October 2028
Primary endpoints
Progression-Free Survival (PFS)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 1 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.