Phase 2 Myeloma Trial, Recruiting NCT07188090 Sponsor: Thomas Jefferson University Condition: Myeloma
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Phase 2 Myeloma Trial, Recruiting

NCT07188090
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older
  • People who are scheduled to receive an autologous stem cell transplant (a procedure using the patient's own stem cells) for multiple myeloma, Hodgkin's lymphoma, or Non-Hodgkin's lymphoma
  • People whose general physical functioning meets a certain minimum level, as measured by a standard medical scoring system called the Karnofsky performance scale (score of 60% or higher)
  • People who meet the specific transplant patient guidelines used at Thomas Jefferson University Hospital's bone marrow transplant program
  • People whose heart is functioning at an adequate level (left ventricular ejection fraction of 40% or higher)
  • People whose lungs are functioning at an adequate level (a breathing test result of 45% or higher of the expected value, adjusted for blood count)
  • People whose liver is functioning within acceptable ranges, based on standard blood test results
  • People whose kidneys are functioning adequately, based on blood and urine measurements (note: this particular kidney requirement may not apply to multiple myeloma patients receiving a specific high-dose chemotherapy called Melphalan — confirm with trial site)
  • People who are willing to use contraception if there is any possibility of becoming pregnant
  • People who are able to give informed consent themselves, or, for those who have difficulty making decisions, people who have a family member or guardian available to assist with and provide consent
  • People with a life expectancy of more than 12 months, not counting the condition being treated with the transplant
  • People who have already gone through stem cell collection using a medication called G-CSF (or a similar drug), either with or without another medication called plerixafor

Who may not be able to join:

  • People with HIV that is not currently under control
  • People with a bacterial infection that is not currently under control
  • People with active disease affecting the brain or central nervous system
  • People who are pregnant or currently breastfeeding
  • People who have another type of cancer, apart from a skin cancer that only needs local (surface-level) treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Xia Bi, MD, MS, Xia.Bi@jefferson.edu

Phone: 215-955-8874

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Thomas Jefferson University
Registry
ClinicalTrials.gov
Start date
16 October 2025
Est. completion
1 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of Engraftment Syndrome

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov