Phase 1 Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with Parkinson's disease for at least 5 years
- Your Parkinson's symptoms, measured during an "off" period (when medication is less effective), reach a certain level of severity as assessed by standard rating scales (confirm with trial site)
- Your symptoms respond positively to a levodopa medication test during an "off" period
- You have been taking a stable, unchanged dose of Parkinson's medication (such as levodopa) throughout the screening period
- You agree to delay any brain surgery related to your Parkinson's treatment during the main part of the study
- You agree not to join any other treatment studies during this trial
- You agree not to receive any vaccines during the main part of the study
- You are willing and able to use reliable contraception from the screening period until at least 52 weeks after receiving the study treatment
- You are able to attend regular follow-up appointments and accurately fill in daily diary cards (a family member, guardian, or caregiver may help with this)
- You are willing to take part voluntarily and have signed a consent form
Who may not be able to join:
- You have a form of Parkinsonism that is not typical Parkinson's disease, or your Parkinson's is caused by another condition
- You have reasons why surgery would not be safe for you, or you have previously had brain surgery
- Your brain MRI scan shows something unusual that suggests a condition other than Parkinson's disease
- You have severe problems with memory or thinking
- You have severe depression or severe anxiety
- You have abnormal liver function results
- You have abnormal blood clotting results
- You have abnormal results from infectious disease screening tests
- You are currently receiving antiviral treatment for hepatitis
- You have an unstable or serious condition affecting your heart, lungs, digestive system, nervous system, blood, immune system, or other major body systems
- You have or have had a cancer diagnosis
- You have a history of severe allergic reactions
- You have taken part in another clinical trial within the past three months
- You have previously received gene therapy
- You have received stem cell treatment within the past 12 months
- You have used another experimental drug within the past 4 weeks
- You received a live vaccine within the past 2 months, or any vaccine within the past 30 days, during the screening period
- You have a history of alcohol dependence or drug addiction
- You are pregnant or breastfeeding
- The trial doctor decides for any other reason that this trial is not appropriate for you (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Jun Liu, MD, Ruijin Hospital
Phone: 021-33588288
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence of dose limiting toxicity (DLT) events; Incidence of Adverse Events (AEs) and Serious Adverse Events (SAEs)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.