Parkinson's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with Parkinson's disease that developed without a known cause (called "idiopathic" Parkinson's disease)
• You already have a specific Medtronic brain stimulation device (Percept PC or Percept RC) implanted, along with specific matching leads and connectors placed on both sides of the brain in the same target area — and the device has been in place for more than 3 months (or more than 1 month if the device was recently replaced)
• Your doctor believes your brain stimulation therapy is helping your Parkinson's symptoms
• Your brain stimulation settings and Parkinson's medications have been stable for at least the last 4 weeks, and are expected to stay stable throughout the study
• Your device is set up in a specific way on at least one side of the brain (using certain electrical contact points — confirm with trial site)
• You are willing and able to attend all required study visits and complete all study tasks, such as memory questionnaires and movement assessments
• You (or your legal representative) can understand and sign a written consent form before the study begins
• You are male, or a female who is not pregnant — if you are a woman who could become pregnant and are sexually active, you must be using or agree to use an acceptable form of birth control
• A brain signal test shows that your implanted device can detect a specific type of brain wave activity (in the 8–30 Hz range) at a certain strength level (confirm with trial site)

Who may not be able to join:

• You or your caregiver are unable to use the handheld patient device that controls the brain stimulator
• You have more than one stimulation lead placed in either side of your brain
• You have any additional brain implants, such as leads placed on the surface of the brain, or other unapproved devices in the brain
• You have more than one implanted stimulator device
• Your implanted device's battery is expected to run out within less than one year
• You score above 25 on a standard depression questionnaire called the Beck Depression Inventory II (confirm with trial site)
• You need, or are likely to need, certain medical treatments including deep heat therapy (diathermy), transcranial magnetic stimulation (TMS), or electroconvulsive therapy (ECT)
• You have a metal implant in your head, such as an aneurysm clip or cochlear implant
• You have, or plan to get, any other implanted electrical medical device in your body, such as a heart pacemaker, defibrillator, or spinal cord stimulator
• You have, or plan to get, an implanted or portable medication pump used to treat Parkinson's disease
• In your doctor's opinion, your neurological examination results would prevent you from safely taking part in the study
• You are currently breastfeeding
• You are under 18 years of age
• You are currently enrolled in, or plan to join, another drug or device study that could affect the results of this trial
• The brain signal readings from your device show interference on all possible measurement pathways, making it impossible to set the device thresholds needed for the study

Important: Always verify eligibility with the trial site directly before applying.