Phase 3 Hypertension Trial, Recruiting (NCT07218783)

Phase 3 Hypertension Trial, Recruiting NCT07218783 Sponsor: SpyGlass Pharma, Inc. Condition: Hypertension

Printed from Voxsanity (voxsanity.com.au) — NCT07218783 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Hypertension

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You have been diagnosed with mild to moderate open-angle glaucoma or high eye pressure (ocular hypertension)
You are planning to have cataract removal surgery
If you are a woman who could become pregnant, you must have a negative pregnancy test at the start of the trial and agree to use contraception during the trial

Who may not be able to join:

You have a serious ongoing health condition that is not well controlled
You have had surgery on your cornea (the front surface of your eye) in the past, such as laser eye surgery or other corrective procedures
Your glaucoma is a type other than open-angle, high eye pressure, pseudoexfoliative, or pigmentary glaucoma
You have previously had surgery inside your eye to treat glaucoma, or have received injections into your eye
You have other eye diseases, conditions, or problems affecting your eyes (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 27 July 2026

Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Paul Yoo, OD, SpyGlass Pharma

Phone: 949-284-6904

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07218783

Sponsor: SpyGlass Pharma, Inc.

Phase: Phase 3

Status: Recruiting

Condition: Hypertension

Trial contact: 949-284-6904

More information: https://clinicaltrials.gov/study/NCT07218783

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You have been diagnosed with mild to moderate open-angle glaucoma or high eye pressure (ocular hypertension)
You are planning to have cataract removal surgery
If you are a woman who could become pregnant, you must have a negative pregnancy test at the start of the trial and agree to use contraception during the trial

Who may not be able to join:

You have a serious ongoing health condition that is not well controlled
You have had surgery on your cornea (the front surface of your eye) in the past, such as laser eye surgery or other corrective procedures
Your glaucoma is a type other than open-angle, high eye pressure, pseudoexfoliative, or pigmentary glaucoma
You have previously had surgery inside your eye to treat glaucoma, or have received injections into your eye
You have other eye diseases, conditions, or problems affecting your eyes (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 27 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 3

Sponsor

SpyGlass Pharma, Inc.

Registry

ClinicalTrials.gov

Start date

15 October 2025

Est. completion

31 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Mean IOP Reduction from Baseline (mmHg); BCDVA 20/40 or better

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov