Phase 3 Colorectal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People whose cancer has spread (metastatic colorectal cancer) confirmed by laboratory testing of a tissue or cell sample
• People who are generally well enough to carry out daily activities with little or no limitation (this is measured using a standard scoring system called ECOG, with a score of 0 or 1)
• People with a life expectancy of at least 6 months
• People who have not yet received any systemic treatment (such as chemotherapy) for their metastatic colorectal cancer
• People who have at least one measurable area of cancer outside the brain that can be tracked on scans

Who may not be able to join:

• People whose cancer has a specific genetic feature known as microsatellite instability-high (MSI-H) or mismatch repair deficiency (dMMR) (confirm with trial site)
• People whose cancer has a specific genetic change called a BRAF V600E mutation
• People who currently have a significant blockage in their digestive system, based on scans or symptoms
• People who have needed a procedure to drain excess fluid from their abdomen in the past 30 days
• People who have previously received immunotherapy or anti-angiogenic therapy (a type of treatment that targets blood vessel growth) for colorectal cancer
• People with a current or past history of inflammatory bowel conditions such as Crohn's disease, ulcerative colitis, or ongoing chronic diarrhoea
• People whose cancer is considered removable by surgery

Important: Always verify eligibility with the trial site directly before applying.