Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People between 10 and 20 years of age
- People who have been diagnosed with major depressive disorder (a condition involving persistent low mood) or bipolar disorder (a condition involving extreme mood swings), confirmed using a standard diagnostic interview
- People who are currently experiencing a moderate to severe episode of depression, measured by a specific rating scale score of 17 or higher
- People (and, for those under 18, one or two parents or guardians) who have given their informed consent after receiving a full explanation of the study
Who may not be able to join:
- People who have received certain brain stimulation treatments (such as rTMS, tDCS, or electroconvulsive therapy) or standard psychological therapy within the 6 months before screening
- People who have been diagnosed with any other mental health condition or personality disorder alongside their main diagnosis
- People who are assessed by a clinician as being at serious risk of suicide
- People who have diabetes, high blood pressure, blood vessel disease, infectious diseases, or other significant physical health conditions
- People with unstable physical health conditions (for example, severe asthma) or neurological conditions such as a past head injury with loss of consciousness for 5 minutes or more, stroke-related conditions, brain tumours, or degenerative brain diseases
- People with an intellectual disability or autism spectrum disorder
- People for whom an MRI scan would not be safe or possible — for example, due to severe claustrophobia, a pacemaker, or metal implants in the body
- People who are currently misusing or dependent on drugs or alcohol
- People who are pregnant or breastfeeding
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Fei Wang, the Affiliated Nanjing Brain Hospital, Nanjing Medical University
Phone: 86-13906900678
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The 17-item Hamilton Depression Rating Scale (HAMD-17); Change in brain functional connectivity measured by resting-state functional MRI; Change in Heart Rate Variability (HRV) via wearable device; Change in daily step count and activity patterns recorded via wearable device; Change in Cytokines (reported in pg/mL); Change in Composite Immune-Inflammatory Ratio Index (unitless)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.