Phase 2 Myeloma Trial, Recruiting NCT07266441 Sponsor: Janssen Research & Development, LLC Condition: Myeloma
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Phase 2 Myeloma Trial, Recruiting

NCT07266441
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been formally diagnosed with multiple myeloma according to recognised international diagnostic standards, with signs of the disease still measurable at the time of screening by a central laboratory
  • People who have already received at least 3 previous treatment courses for multiple myeloma, including one from each of three specific drug types: a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody treatment
  • People whose multiple myeloma has come back, gotten worse, or did not respond to their most recent treatment, as determined by their doctor using standard international criteria
  • People who have stopped all other cancer treatments (including certain types of radiotherapy) or experimental treatments before joining the trial
  • People whose general health and ability to carry out daily activities falls within a specific range on a standard medical scale (scored 0 to 2 out of 4) at the time of screening and before starting the trial treatment

Who may not be able to join:

  • People with known or suspected allergies or sensitivities to any ingredients in the trial drug, JNJ-79635322
  • People who have had major surgery within 2 weeks before the first trial dose, or who have major surgery planned during the treatment period of the trial
  • People who have active or previously confirmed involvement of multiple myeloma in the brain or spinal fluid, or who show clinical signs of the disease affecting the membranes around the brain or spinal cord
  • People who have a condition called leptomeningeal disease, where cancer has spread to the fluid and membranes surrounding the brain and spinal cord
  • People who have, or have previously had, a second type of cancer whose natural course or treatment could likely interfere with the trial's results or the safety assessment of the study treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 844-434-4210

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
8 February 2026
Est. completion
14 June 2027

Where this trial is recruiting

🇨🇳 China 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan 🇵🇱 Poland 🇰🇷 South Korea Turkey (Türkiye) 🇺🇸 United States

Primary endpoints

Overall Response Rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov