Phase 2 Hypertension Trial, Recruiting NCT07267260 Sponsor: King Edward Medical University Condition: Hypertension
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Phase 2 Hypertension Trial, Recruiting

NCT07267260
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 75 years old (any gender)
  • People who have been diagnosed with liver cirrhosis (scarring of the liver), confirmed through medical tests, blood work, or scans
  • People who have enlarged veins in the food pipe (esophageal varices) that have been identified as needing a procedure to treat them with small rubber bands (called endoscopic variceal band ligation)
  • People who are able and willing to sign a consent form in either English or Urdu
  • People who are willing to follow the study requirements, including taking the study medication and attending follow-up scope procedures

Who may not be able to join:

  • People who have had previous surgery on the stomach or food pipe
  • People who have a known allergy or medical reason to avoid the study drug (vonoprazan) or its ingredients
  • Women who are pregnant or currently breastfeeding
  • People who are unable to communicate in the languages used in the study or are unable to cooperate with study procedures
  • People who are critically unwell, including those who require intensive care unit (ICU) admission, need a breathing machine, or have a significantly reduced level of consciousness (confirm with trial site)
  • People who are actively bleeding from the digestive tract at the time of joining the study
  • People who have a cancer involving the upper digestive tract (such as the stomach or food pipe)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +923337692728

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
King Edward Medical University
Registry
ClinicalTrials.gov
Start date
16 December 2025
Est. completion
30 January 2026

Where this trial is recruiting

🇵🇰 Pakistan

Primary endpoints

Incidence of Post-Endoscopic Variceal Band Ligation (EVBL) Ulcers

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov