Phase 4 Atrial Fibrillation Trial, Recruiting NCT07287345 Sponsor: Ayesha Ather Condition: Atrial Fibrillation
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Phase 4 Atrial Fibrillation Trial, Recruiting

NCT07287345
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You are scheduled to have a planned heart bypass surgery (where surgeons use blood vessels to reroute blood around blocked arteries in the heart)

Who may not be able to join:

  • You have a history of an irregular heart rhythm condition called atrial fibrillation
  • Your bypass surgery is planned to be performed while your heart is still beating (known as "off-pump" surgery)
  • You are currently taking a medication called colchicine for any reason
  • You have had a bad reaction to colchicine in the past, such as a rash, hives, itching, or blistering or peeling skin, with or without fever
  • Your heart surgery is needed urgently or in an emergency situation
  • You need or have needed a special life-support machine called ECMO (a machine that temporarily does the work of the heart and lungs) before or after surgery
  • You have had a heart transplant
  • You currently use a mechanical device to help your heart pump blood (called an LVAD)
  • Your kidneys are not working well enough, based on a specific blood test result (confirm with trial site)
  • You have raised levels of a muscle-related protein in your blood before surgery, or you have a known muscle disease (confirm with trial site)
  • You have severe liver disease or abnormal liver blood test results above a certain level (confirm with trial site)
  • You have a long-term bowel or intestinal condition, or a blood disorder (confirm with trial site)
  • You are not able to speak English
  • You are pregnant or currently breastfeeding (applies to women)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Sibu Saha, MD, University of Kentucky

Phone: 8592184157

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Ayesha Ather
Registry
ClinicalTrials.gov
Start date
16 January 2026
Est. completion
30 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Inflammatory markers; Rate of post-operative atrial fibrillation (POAF)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov