Early Phase 1 Myeloma Trial, Recruiting NCT07294625 Sponsor: The First Affiliated Hospital with Nanjing Medical University Condition: Myeloma
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Early Phase 1 Myeloma Trial, Recruiting

NCT07294625
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing to take part voluntarily, have been fully informed about the study, and have signed a consent form before any study-related procedures begin.
  • People aged 18 or older.
  • People whose general health and ability to carry out daily activities is rated as fully active or restricted only in physically strenuous activity (this is measured using a standard scale called the ECOG scale, scored 0 or 1).
  • People who have at least one area of disease that can be measured on scans or tests.
  • People whose multiple myeloma has come back after treatment or has stopped responding to treatment.
  • People whose life expectancy is at least 3 months.
  • People whose blood and other lab test results meet the required levels at the screening visit (confirm with trial site for specific values).
  • People whose heart, liver, kidneys, and other organs are functioning well enough to meet the trial's requirements (confirm with trial site for specific criteria).

Who may not be able to join:

  • People who have recently received other cancer treatments and have not waited long enough since finishing them (confirm with trial site for specific timeframes).
  • People who have previously received a treatment that targeted a protein called GPRC5D.
  • People who test positive for hepatitis B, hepatitis C, or HIV.
  • People with a known serious allergic reaction or intolerance to any ingredient in the study drug, including a substance called DMSO, or people who have a history of severe allergic reactions that required strong medicines such as steroids to manage.
  • People whose overall health situation is considered by the trial doctor to make participation unsuitable for any reason.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Phone: 025-68306091

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
10 December 2025
Est. completion
31 March 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Incidence, severity and type of TEAEs (Treatment-emergent Adverse Events); Pharmacokinetics in peripheral blood; Pharmacokinetics in bone marrow; The recommended Phase II dose (RP2D) for this cell

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov