Phase 2 Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with Parkinson's disease within the last 5 years, using recognised medical diagnostic guidelines.
- A special brain scan (called a DaTscan) has confirmed changes in the part of the brain affected by Parkinson's disease.
- Your Parkinson's symptoms are at a mild to moderate stage (below a certain level on a standard rating scale used by doctors).
- Your Parkinson's medication has been stable and not needed any changes for at least 2 weeks.
- You are between 40 and 80 years old at the time of joining the trial.
Who may not be able to join:
- You have dementia or another brain/nerve condition in addition to Parkinson's disease.
- Your condition has been identified as an atypical form of parkinsonism (such as PSP, MSA, CBD, vascular parkinsonism, or parkinsonism caused by medication).
- Your Parkinson's disease is known to be caused by a specific gene change (although one particular gene variation called GBA1 is still accepted).
- You have a psychiatric (mental health) condition that could make it difficult to take part in the study.
- You have a serious physical illness that would prevent you from fully participating in the trial.
- You have taken D-serine supplements within the 90 days before joining the trial.
- You have a metabolic condition, cancer, or another serious physical or mental health condition at the start of the trial.
- You are currently pregnant, planning to become pregnant, or planning a pregnancy during the trial period.
- You have significant memory or thinking difficulties, based on a standard cognitive test score below 20.
- You weigh less than 45 kg (approximately 99 lbs or 7 stone).
- A urine test shows a certain protein-to-waste ratio in your kidneys is too high (confirm with trial site).
- You have moderate or advanced kidney disease, based on a blood test measuring how well your kidneys are filtering (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 55975061
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in MDS-UPDRS Total Score (sum of Parts I-III).
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.