Phase 3 Parkinson's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 years or older
• People who have been diagnosed with idiopathic Parkinson's disease (Parkinson's that has no known cause) using internationally recognised diagnostic guidelines
• People whose Parkinson's medication has been stable and at the best-possible dose for at least four weeks before the trial starts, and who are expected to remain stable throughout the trial
• People who experience freezing of gait (sudden episodes where the feet feel "stuck" to the ground) on a daily basis
• People who are able to walk 10 metres without assistance while their Parkinson's medication is working well
• People who are able to sign a written consent form in line with research regulations
• People who are willing and able to attend and complete all assessments required by the trial

Who may not be able to join:

• People who are currently in another clinical trial, or who have participated in one within the past three months
• People who cannot have an MRI scan for any reason — for example, due to claustrophobia, or because they have metal devices inside their body such as a deep brain stimulator, infusion pump, or pacemaker
• People who have another medical condition that significantly affects their ability to walk, such as bone or joint problems
• People with severe difficulties with thinking or memory that would make it hard to follow the trial's requirements
• People with active psychosis (such as hallucinations or delusions) that would make it hard to follow the trial's requirements
• People with serious heart conditions, including very high blood pressure, heart failure, blocked arteries, angina, significant heart disease present from birth, heart muscle disease, previous heart attack, potentially life-threatening irregular heartbeats, long QT syndrome, or certain inherited heart rhythm disorders — where the trial doctor considers these to be a significant safety concern
• People with serious brain blood vessel conditions, such as a brain aneurysm or a recent or significant stroke
• People with liver or kidney problems that the lead trial doctor considers would make participation unsafe
• People with a specific type of eye pressure condition called narrow-angle glaucoma
• People who have, or have had, a rare adrenal gland tumour called a phaeochromocytoma
• People who are currently taking medications that affect the noradrenaline system (noradrenergic agents) (confirm with trial site)
• People who are currently taking certain medications that affect how the body processes drugs, including some antidepressants (SSRIs), quinidine, or terbinafine (an antifungal medicine)
• People taking high doses of salbutamol or similar medicines (called beta-2 agonists), where the lead trial doctor considers this would affect safe participation
• People who are pregnant or breastfeeding
• People who have a known allergy or sensitivity to atomoxetine (the medicine being studied in this trial)

Important: Always verify eligibility with the trial site directly before applying.