Colorectal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older who are generally well enough to carry out daily activities (rated on a standard medical scale as 0, 1, or 2 out of 4)
• People with a confirmed diagnosis of stage II or stage III colorectal cancer (a type of bowel cancer) based on laboratory testing of tissue
• People whose tumor has been confirmed through laboratory testing to have a specific feature called "mismatch repair deficiency" or "high microsatellite instability," which relates to how the cancer's DNA repairs itself
• People who have signed a consent form agreeing to take part in the trial

Who may not be able to join:

• People who have a history of other serious health conditions that would make surgery unsafe or unsuitable
• People who have any of the following conditions: an active autoimmune disease, an active infection, inflammatory bowel disease, a need for long-term steroid or immune-suppressing medications, a history of immune system deficiency, a history of organ transplant or stem cell transplant, or severe scarring or inflammation of the lungs
• People with a known allergy or sensitivity to the study drug (tislelizumab) or to similar drugs that work on the immune system (called PD-1/PD-L1 treatments)
• People who the trial doctors consider unsuitable for any other reason not listed above (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.