Colorectal Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 75 years
- People who have been diagnosed with rectal cancer very close to the anal sphincter muscles, where a type of surgery called Intersphincteric Resection (ISR) is the recommended surgical approach
- People who have had a temporary ileostomy (a surgically created opening in the abdomen to divert waste) as a precaution during their cancer surgery
- People whose surgical team has planned to reverse the temporary stoma within 6 months of the ISR surgery
- People whose bowel was reconnected during surgery using either a hand-sewn or stapled joining technique
- People who have a strong personal preference for surgery that preserves the sphincter muscles
- People who are able to understand the trial information and are willing to sign a consent form
Who may not be able to join:
- People whose cancer does not meet the medical criteria for ISR surgery
- People who have more than one primary colorectal cancer at the same time
- People who received radiation therapy before their main surgery (neoadjuvant radiotherapy)
- People whose cancer progresses or who pass away during the period after surgery
- People who develop serious complications at the surgical join site after the operation, such as leakage or narrowing
- People whose stoma reversal surgery ends up taking place more than 6 months after the ISR procedure
- People who need to take antibiotics for a long period — more than 3 months
- People with a known allergy to the probiotic product Clostridium butyricum (MIYA) Tablets or any of its ingredients
- People who are using other probiotic products at any point during the study period
- People who also have inflammatory bowel disease (such as Crohn's disease or ulcerative colitis)
- People with a history of neurological or psychiatric conditions, including Parkinson's disease, Alzheimer's disease, stroke, epilepsy, major depression, or other brain or psychiatric disorders
- People who are pregnant or breastfeeding
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Xiang Jianbin, Doctor, Huashan Hospital
Phone: +86-13764030915
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Low Anterior Resection Syndrome Score（LARS Score）; microbial diversity
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.