Parkinson's Disease Trial, Recruiting NCT07376278 Sponsor: Hong Kong University of Science and Technology Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT07376278
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been formally diagnosed with Parkinson's disease using the Movement Disorder Society's established diagnostic guidelines
  • People who have been recommended for deep brain stimulation (DBS) surgery by their medical team, following standard local clinical guidelines
  • People who continue to have significant movement problems despite taking the best available medication
  • People whose movement score (measured using a standard Parkinson's rating scale called UPDRS) is above a certain level when not taking medication (confirm with trial site for exact score)
  • People whose Parkinson's symptoms are at a certain stage of severity when not taking medication, as measured by a standard staging system (confirm with trial site)
  • People whose movement symptoms respond well to levodopa medication, with at least a 33% improvement shown in testing
  • People aged 75 years or younger
  • People with no major surgical risks or serious health conditions that would significantly shorten life expectancy
  • People with no significant mental health conditions or problems with memory and thinking
  • People with no abnormal findings on brain scans that might suggest a different condition rather than Parkinson's disease

Who may not be able to join:

  • People who are unwilling to have blood samples taken for the study
  • People whose Parkinson's-like symptoms appear to be caused by heavy metal exposure
  • People with a history of certain other neurological or serious health conditions, including other brain or nervous system diseases, brain infections, conditions such as multiple sclerosis, a cancer diagnosis within the last 10 years, stroke, HIV infection, a systemic autoimmune disease, or alcohol or other substance dependence
  • People who do not pass the pre-surgery assessment required before DBS, or who are unwilling to undergo DBS surgery

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Nancy Ip, The Hong Kong University of Science and Technology

Phone: 852-23587304

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Hong Kong University of Science and Technology
Registry
ClinicalTrials.gov
Start date
5 February 2026
Est. completion
1 February 2036

Where this trial is recruiting

Hong Kong

Primary endpoints

Blood proteomic profile; Blood transcriptomic profile; Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS); Hoehn and Yahr (H&Y) stage

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov