Peripheral Neuropathy Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 70 years old who have signed a consent form to participate
• People diagnosed with early or intermediate-stage breast cancer (confirmed by tissue testing) that has not come back after previous treatment
• People whose treatment plan includes a course of chemotherapy using taxane-based drugs (either a 4-cycle or single-cycle plan)
• People who have not previously had any chemotherapy, immunotherapy, or hormone therapy for breast cancer
• People whose heart scan (echocardiogram) shows the heart is pumping normally
• People who are generally able to carry out daily activities with no more than mild limitations (confirm with trial site regarding specific ECOG score requirement)
• People who have no mental health or thinking difficulties that would prevent them from understanding and completing questionnaires
• People who have no signs of nerve damage caused by chemotherapy at the start of the trial
• People whose blood counts and organ function (including liver, kidneys, and blood cells) meet specific healthy ranges set by the trial
• Women who could become pregnant must agree to use reliable contraception starting 7 days before the first treatment through 24 weeks after treatment ends, and must have a negative blood pregnancy test within 7 days before the first treatment

Who may not be able to join:

• People with active infections, skin sores on the hands or feet, or any medical reason that prevents them from receiving chemotherapy, acupuncture, or compression therapy
• People who have previously been treated with certain nerve-affecting chemotherapy drugs such as taxanes, oxaliplatin, platinum-based drugs, or vincristine
• People who have had acupuncture treatment for any reason within the past month
• People with conditions that can already cause nerve damage or similar symptoms, such as diabetes, alcoholism, kidney disease, autoimmune conditions, rheumatoid arthritis, neck spine problems, severe mental illness, or severe physical trauma
• People with Raynaud's syndrome, sensitivity to cold, poor blood circulation in the limbs, or hand-foot syndrome
• People currently taking medications that could hide nerve damage symptoms, such as certain antidepressants (SSRIs, SNRIs, tricyclics) or B-complex vitamins
• People who have swelling caused by lymph fluid (lymphedema) in areas where acupuncture would be applied
• People who have a fear of electroacupuncture or an allergy to stainless steel needles
• People with serious non-cancer health conditions that may make it difficult to follow the trial treatment plan
• People who are currently receiving other cancer treatments or participating in another clinical trial
• People with dementia, cognitive difficulties, or psychiatric conditions that affect their ability to understand and give informed consent
• People with a known allergy or medical reason that prevents them from undergoing the trial procedures
• People with serious or uncontrolled heart problems, including moderate-to-severe heart failure, unstable chest pain, a heart attack within the past year, or significant heart rhythm problems requiring treatment
• People who have a cardiac pacemaker
• People with known bleeding or clotting disorders, such as haemophilia, low platelet counts, or other conditions affecting the blood's ability to clot

Important: Always verify eligibility with the trial site directly before applying.