Printed from Voxsanity (voxsanity.com.au) — NCT07393048 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Colorectal Cancer Trial, Recruiting
NCT07393048
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have agreed in writing to take part in the study voluntarily
- You are between 18 and 75 years old (any sex)
- Your doctors have confirmed through a tissue sample (biopsy) that you have rectal cancer of a specific type called adenocarcinoma
- Your cancer has been assessed by MRI scan as being at a middle or advanced local stage (Stage II or III)
- Your tumor is located within 10 cm of the opening of the back passage (anus)
- Your cancer can be removed by surgery
- You are able to swallow tablets normally
- You are generally well enough to carry out light daily activities (confirm with trial site)
- You have not received any previous treatment for your rectal cancer (no radiotherapy, chemotherapy, or surgery)
- You are planned to have surgery after completing the pre-surgery treatment used in this trial
- There is no medical reason preventing you from having surgery
- Your blood tests show that your major organs (such as liver, kidneys, and blood cells) are working normally
Who may not be able to join:
- You have had an allergic reaction to monoclonal antibody medicines, to a drug called tislelizumab, or to capecitabine (a chemotherapy tablet)
- You have already received any cancer treatment such as surgery, radiotherapy, chemotherapy, targeted therapy, or immunotherapy
- You currently have, or have previously had, a disease where your immune system attacks your own body (an autoimmune disease)
- You have a weakened immune system, including HIV infection, any other immune deficiency condition, or you have had an organ transplant or bone marrow transplant from a donor
- You have significant heart problems that are not well controlled, such as moderate-to-severe heart failure, unstable chest pain (angina), a heart attack within the past year, or serious irregular heartbeats
- You have been diagnosed with another cancer in the last 5 years — although certain very low-risk skin cancers or early-stage cervical changes that have been fully treated may still be considered (confirm with trial site)
- You are currently pregnant or breastfeeding
- You have other serious health conditions, mental health disorders, substance misuse issues, or personal circumstances that the study doctors feel could affect your safety or ability to take part fully (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Recruiting
Phase
Not Applicable
Sponsor
Beijing Friendship Hospital
Registry
ClinicalTrials.gov
Start date
15 February 2026
Est. completion
31 December 2028
Where this trial is recruiting
🇨🇳 China
Primary endpoints
Complete Response (CR) rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.