Parkinson's Disease Trial, Recruiting NCT07399496 Sponsor: Medical University of South Carolina Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT07399496
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 45 and 85 years old
  • You have been diagnosed with Parkinson's Disease
  • You have scored 37 or higher on a scale that measures apathy or motivation levels (confirm with trial site)
  • Your Parkinson's medications have not changed recently and are considered stable
  • You have a family member, friend, or caregiver who can provide information about you as part of the study

Who may not be able to join:

  • You have a medical reason why you cannot safely have an MRI scan or a brain stimulation procedure called TMS (confirm with trial site)
  • You have significant memory or thinking difficulties, based on a standard cognitive test score below 21
  • You have been diagnosed with certain mental health conditions, including bipolar disorder, schizophrenia, or a current substance use disorder
  • You have a history of seizures or epilepsy
  • You have had recent thoughts of ending your life or have made a suicide attempt in the past year, based on a standard safety assessment
  • You are currently pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
1 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

TMS adherence; Frequency and Severity of TMS-Induced Side effects (TMS tolerability and acceptability); Apathy severity as measured by the Lille Apathy Rating Scale; Target engagement (dmPFC network modulation)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov