Parkinson's Disease Trial, Recruiting NCT07403799 Sponsor: Bial - Portela C S.A. Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT07403799
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are able to understand what the study involves and are willing to sign a consent form to take part.
  • You are 30 years old or older.
  • You have been diagnosed with Parkinson's disease based on recognised medical diagnostic guidelines.
  • Your Parkinson's disease is rated as mild to moderate in severity (stages 1 to 3 on a standard rating scale used by doctors).
  • You have been taking a Parkinson's medication containing levodopa (combined with another drug that helps it work) for at least 1 year.
  • You have been experiencing a "wearing off" effect — where your medication stops working before your next dose is due — for less than 2 years.
  • Your doctor has already decided, independently of this study, to start you on a medication called opicapone as part of your normal treatment.

Who may not be able to join:

  • You have a form of Parkinsonism that is not Parkinson's disease (for example, a different condition that causes similar symptoms).
  • You are currently taking part in another clinical trial involving an experimental drug, or you finished such a trial within the last 30 days.
  • You have a medical reason why you should not take opicapone, based on the official prescribing guidelines for that medication (confirm with trial site).
  • Your doctor considers that you have dementia.
  • You are currently taking a type of medication known as a COMT inhibitor (a different class of Parkinson's drug — confirm with trial site if unsure whether this applies to you).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Bial - Portela C S.A.
Registry
ClinicalTrials.gov
Start date
8 July 2025
Est. completion
31 October 2028

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Patient Global Impression of Change (PGI-C) score improvement (minimally, much or very much), no change or worsening (minimally, much or very much) 12 months after start of treatment.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov