Atrial Fibrillation Trial, Recruiting NCT07405359 Sponsor: Edward Gerstenfeld, MD Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT07405359
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older at the time of their pre-procedure visit
  • People who have persistent atrial fibrillation (an irregular heart rhythm that has lasted continuously for at least 7 days), confirmed by a continuous heart monitor, two heart tracings (ECGs) taken more than 7 days apart, or at least 3 procedures to restore normal heart rhythm
  • People who have been recommended for, and are interested in, having a small heart monitor device implanted under the skin to track heart rhythm after the ablation procedure
  • People who are willing and able to follow the study requirements and have provided written consent to participate

Who may not be able to join:

  • People who have previously had an ablation procedure inside or on the surface of the heart, except for certain specific prior procedures (confirm with trial site)
  • People who have had a stroke or a temporary stroke-like episode (sometimes called a "mini-stroke") within the past six months
  • People who have had bleeding in their digestive system within the past three months
  • People who already have a pacemaker or implanted heart defibrillator device
  • People whose atrial fibrillation has been continuously present for more than three years
  • People whose left upper heart chamber is larger than a certain size as measured by imaging (confirm with trial site)
  • People who have a device implanted to close a hole between the upper chambers of the heart
  • People who currently have a blood clot in the upper left chamber of the heart
  • People who have a device closing off part of the heart called the left atrial appendage that was placed less than 6 months ago, has a leak, or has had a clot on it previously
  • People who have a clip or mechanical replacement on certain heart valves (the mitral or tricuspid valves)
  • People who have a condition where the heart muscle is abnormally thick (hypertrophic cardiomyopathy)
  • People for whom accessing the large blood vessels in the groin area is not medically suitable
  • People who have a structural heart defect present from birth that has left an ongoing abnormality
  • People who cannot take, or are unwilling to take, blood-thinning medication
  • People who are pregnant
  • People whose heart pumping strength is below a certain level as measured by imaging (confirm with trial site)
  • People whose kidney function is below a certain level as measured by a blood test (confirm with trial site)
  • People whose life expectancy is predicted to be less than one year
  • People who do not wish to have the small monitoring device implanted, or who have an allergy to it

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Edward Gerstenfeld, MD, MS, University of California, San Francisco

Phone: 415-514-7310

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Edward Gerstenfeld, MD
Registry
ClinicalTrials.gov
Start date
3 April 2026
Est. completion
14 August 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

AF freedom

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov