Phase 1 Myeloma Trial, Recruiting NCT07409246 Sponsor: AbbVie Condition: Myeloma
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Phase 1 Myeloma Trial, Recruiting

NCT07409246
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have multiple myeloma that has either come back after treatment (relapsed) or stopped responding to treatment (refractory), as confirmed by their doctor using standard international guidelines.
  • People whose myeloma has measurable signs of the disease in their blood or urine, detected within 28 days before enrolling — this includes specific protein levels in the blood or urine, or abnormal levels of certain proteins called free light chains.
  • People who have already been through three or more previous rounds of treatment, including at least one treatment from each of these three types: a proteasome inhibitor, an immunomodulatory drug (IMiD), and an anti-CD38 therapy — and for whom other available treatments are no longer suitable or accessible.

Who may not be able to join:

  • People who have a known history of multiple myeloma that has spread to the brain or spinal cord (the central nervous system).
  • People who have a history of certain lung conditions, including idiopathic pulmonary fibrosis, organising pneumonia, or inflammation of the lungs caused by medication or of unknown origin.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Registry
ClinicalTrials.gov
Start date
27 February 2026
Est. completion
1 November 2031

Where this trial is recruiting

🇮🇱 Israel 🇯🇵 Japan 🇺🇸 United States

Primary endpoints

Number of Participants With Adverse Events (AE); Number of Participants With Clinically Significant Changes From Baseline in Clinical Laboratory Parameters; Number of Participants With Clinically Significant Changes From Baseline in Vital Sign Parameters; Number of Participants With Clinically Significant Changes From Baseline in Electrocardiograms (ECG)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov