Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been clinically diagnosed with hereditary spastic paraplegia (genetic confirmation is helpful but not required)
- People whose medications for spasticity and other neurological symptoms have stayed the same for at least 4 weeks before joining the study
- People who are able to attend study visits and complete assessments, whether or not they use a mobility aid
- People who can walk at least 10 metres with or without a walking aid (if they are able to walk)
- People who use a wheelchair and are able to complete seated movement and transfer tasks required for the study assessments
- People who are able to understand and follow study instructions in English and can give their informed consent to participate
Who may not be able to join:
- People who have an implanted electronic device, such as a pacemaker, deep brain stimulator, or intrathecal pump
- People with serious heart or lung disease that could make participation unsafe
- People who have open wounds or severe skin conditions in the areas where electrodes would be placed
- People who are pregnant or planning to become pregnant during the study period
- People who have been diagnosed with Primary Lateral Sclerosis (PLS) or another condition affecting walking, such as stroke, multiple sclerosis, or who have had recent leg surgery
- People who are unable to complete basic movement or mobility assessments even when using their usual mobility aid (confirm with trial site)
- People with cognitive or psychiatric conditions that make it difficult to give informed consent or follow study instructions
- People who have an active or recent urinary tract infection (UTI) at the time of enrolling in the study
- People who have been diagnosed with epilepsy
- People who are currently taking part in another clinical trial that could affect their movement or spasticity
- People whose spasticity or movement medications (such as baclofen, tizanidine, or botulinum toxin injections) have changed in the 4 weeks before joining
- People who are expecting to start or change spasticity or mobility treatments during the study period
- People whose overall health situation is judged by the study investigator to pose additional risks or could affect the study results (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Rahul Sachdeva, PhD, University of Kentucky
Phone: 8592574888
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in 10-Meter Walk Test (10MWT); Change in 6- Minute Walk Test (6MWT); Change in Modified Ashworth Scale (MAS); Change in Spastic Paraplegia Rating Scale (SPRS)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.