Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with type 1 or type 2 diabetes, as defined by major international health organisations
• People whose HbA1c blood sugar level result is 12% or below (this is a measure of average blood sugar over several months)
• People whose study eye has swelling in the central part of the retina (a condition called diabetic macular oedema) that meets specific measurements on a retinal scan, and whose vision in that eye falls within a certain range as measured by a standardised letter chart (confirm specific vision score range with trial site)

Who may not be able to join:

• People whose diabetes is currently untreated, or who only recently started diabetes tablets or insulin within the 90 days before the trial begins
• People who are pregnant, breastfeeding, or planning to become pregnant during the study or within a period when contraception is required
• People with uncontrolled high blood pressure
• People whose study eye has previously received any injections or implants into the eye (such as anti-VEGF medicines or steroid treatments) — this applies to certain parts of the trial; other parts of the trial have more specific rules about timing of past treatments (confirm which rules apply with the trial site)
• People who have a history of certain types of eye inflammation, including inflammation of the middle layer of the eye, the gel inside the eye, or the white outer layer of the eye, in either eye
• People who currently have active inflammation inside either eye
• People whose study eye has ever had, or currently has, an advanced form of diabetic eye disease known as proliferative diabetic retinopathy

Important: Always verify eligibility with the trial site directly before applying.