Early Phase 1 Hypertension Trial, Recruiting NCT07425535 Sponsor: Johns Hopkins University Condition: Hypertension
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Early Phase 1 Hypertension Trial, Recruiting

NCT07425535
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged over 30 of any sex or ethnic background may be considered.
  • People who have no history of open-angle glaucoma (a specific type of eye pressure condition) may be considered.
  • People whose eye examination by a glaucoma specialist showed no signs of open-angle glaucoma may be considered.
  • People whose specialized eye scan (a test that measures the nerve fibers at the back of the eye) came back normal may be considered.
  • People who have a condition affecting the optic nerve (the nerve connecting the eye to the brain) may be considered.
  • Both people suspected of having glaucoma damage and those who already have confirmed glaucoma damage may be considered.
  • If both eyes meet the trial's criteria, both eyes may be included in the study.

Who may not be able to join:

  • People who are unable to sit upright due to a physical disability.
  • People whose eye clarity is affected by clouding, corneal scarring, cataracts, or bleeding inside the eye that would prevent clear imaging.
  • People who are unable to keep their eyes open comfortably during the imaging procedure.
  • People who are unable to accurately perform eye pressure measurements at home during the practice/certification stage.
  • People whose specialized eye scan (OCT) results are not considered reliable.
  • People who have any form of glaucoma (confirm with trial site, as this appears to conflict with some inclusion criteria above).
  • People with very high short-sightedness, defined as a prescription stronger than -8.
  • People who have had laser or surgical vision correction, or have a corneal disease or abnormal corneal shape, that would make home eye pressure readings difficult to interpret.
  • People who are unable to understand English, or who have a language or hearing impairment.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Harry Quigley, MD, Johns Hopkins University

Phone: 410 955 6051

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
24 June 2026
Est. completion
1 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Optic nerve head strain

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov