Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are at least 18 years old
- People whose overall health condition is stable
- People who have a spinal cord injury (SCI) that has not gotten worse neurologically since at least 6 months after the injury, or in the 6 months before screening
- People whose spinal cord injury is classified as motor-complete (meaning significant loss of movement), rated as grade "A," "B," or "C" on a standard spinal cord injury scale, with the injury located above a specific spinal level (T1) (confirm with trial site)
- People whose spinal cord injury occurred at least 12 months before entering the study
- People who have symptoms of low blood pressure when changing positions (such as dizziness or lightheadedness), confirmed by a symptom assessment score above zero
- People whose kidneys are functioning normally, based on specific blood test results within defined ranges (confirm with trial site)
- People who are able to give informed consent and follow instructions for the study
Who may not be able to join:
- People with serious lung or heart disease that is not related to their spinal cord injury
- People who depend on a ventilator to breathe
- People with painful muscle or bone problems that could interfere with testing or the stimulation used in the trial
- People with a bone fracture that has not fully healed and could interfere with testing or stimulation
- People with a joint contracture (stiffness or tightening) that has not healed and could interfere with testing or stimulation
- People with a pressure sore that has not healed and could interfere with testing or stimulation
- People with depression or psychiatric conditions that are clinically significant and currently untreated
- People who are currently misusing drugs or substances
- People who have been diagnosed with cancer
- People with a very high BMI (over 40) and at least one of the following: type 2 diabetes confirmed by two blood tests, or high blood pressure (consistently 140/90 mmHg or above, or currently taking blood pressure medication)
- People with a blood clot in a deep vein (DVT), whether acute or ongoing
- People whose low blood pressure is caused by a condition unrelated to their spinal cord injury, such as anaemia, fluid imbalance, or hormonal or neurological disorders
- People with a significant problem affecting the oesophagus or digestive system
- People who are currently pregnant (applies to females of childbearing potential)
- People with any other major medical condition that the trial site determines would make testing or stimulation unsafe (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Alexander Ovechkin, University of Louisville
Phone: 1-502-581-8675
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Baroreflex Sensitivity; Renal Artery Systolic Velocity (Right and Left); Plasma Renin Activity; Angiotensin Converting Enzyme; Aldosterone
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.