Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any gender
• People who have been diagnosed with pancreatic cancer (specifically the type that starts in the lining of the pancreatic ducts) that has spread to the liver
• People whose general physical functioning falls within a certain range, meaning they are able to carry out at least some daily activities (rated 0 to 2 on a standard medical scale)
• People whose blood test results show that their immune cells, red blood cells, and platelets are at sufficient levels
• People whose liver, kidney, and other organ function blood tests fall within acceptable ranges (confirm specific values with trial site)
• People whose heart function tests, including an ECG and heart pump strength measurement, are within normal or near-normal ranges
• People who have finished surgery, radiation, chemotherapy, or other cancer treatments at least 3 weeks before joining, and whose side effects from those treatments have mostly resolved
• People who are willing to sign a consent form and agree to follow-up appointments to check on their health over time

Who may not be able to join:

• People who have fluid build-up in the abdomen that requires medical treatment, unless it has been stable for more than 4 weeks after draining
• People with serious gastrointestinal conditions such as bleeding, infection, a hole in the gut wall, blockage, or significant diarrhoea
• People whose pain is not well controlled by standard pain medication, rating 4 or higher on a standard pain scale
• People who have had a second, separate cancer within the past 5 years (some types of fully treated skin cancers or cancers that have not come back in 5 years may still be eligible — confirm with trial site)
• People with serious heart or blood vessel conditions that are not well controlled, such as severe heart failure, unstable chest pain, a heart attack or stroke within the past 6 months, certain heart rhythm problems, or high blood pressure that has not responded to treatment
• People with active hepatitis B infection at certain levels detected in blood tests
• People who have an active infection or an unexplained fever above 38.5°C at the time of screening or when treatment would begin (fevers clearly caused by the tumour may be assessed differently by the trial doctor)
• Women who are pregnant or breastfeeding
• Women who could become pregnant and have a positive pregnancy test during the screening period (both male and female participants are expected to use reliable contraception during the trial and for 3 months after the last dose)
• People with other medical or personal circumstances that the trial doctor believes could affect their ability to participate safely or make the results harder to interpret
• People whose expected survival is estimated to be 3 months or less

Important: Always verify eligibility with the trial site directly before applying.