Phase 2 Gout Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 75 years old (inclusive) at the time of signing the consent form.
• You have been diagnosed with gout (based on specific medical guidelines) for at least 1 year, AND either you have had problems tolerating or been advised against taking allopurinol or febuxostat, OR a previous uricase treatment did not work well enough or caused problems for you.
• Your uric acid level in your blood is above 6.0 and below 10.5 mg/dL, confirmed at two separate screening appointments.
• If you are a woman who could become pregnant, you must have a negative pregnancy test at two points during screening and must not be breastfeeding.
• If you could father or become pregnant, you must agree to either abstain from heterosexual sex or use an acceptable form of birth control from signing the consent form until 30 days after your last dose of the trial drug.

Who may not be able to join:

• You have had kidney stones within the past year.
• You have had a cancer diagnosis in the last 5 years, except for certain treated skin cancers (basal or squamous cell carcinoma).
• You have a known history of drug misuse, tested positive for drugs at the first screening visit, or have a recent history of alcohol misuse.
• You have HIV, Hepatitis B, or Hepatitis C, or tested positive for these during screening.
• You have any significant health condition that, in the trial doctor's opinion, could affect your safety, your ability to follow the trial requirements, or the accuracy of the trial results (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.