Phase 3 Lung Cancer Trial, Recruiting NCT07541170 Sponsor: Hoffmann-La Roche Condition: Lung Cancer
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Phase 3 Lung Cancer Trial, Recruiting

NCT07541170
Recruiting Phase 3

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are fully active or have only minor restrictions in daily physical activity (as measured by a standard oncology scale called ECOG, with a score of 0 or 1).
  • People who have been diagnosed through a tissue or cell sample with a specific type of lung cancer called non-small cell lung cancer (NSCLC), at a stage between Stage II and Stage IIIB, of either squamous or non-squamous type.
  • People whose lung cancer was completely removed through surgery.
  • People who previously received a type of immunotherapy drug (pembrolizumab or nivolumab) combined with chemotherapy before their surgery.
  • People who are enrolled into the trial within 12 weeks of their surgery date.
  • People who have no signs of cancer returning or spreading after surgery.
  • People whose cancer has been confirmed to have a specific genetic change called a KRAS G12C mutation.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose cancer showed a complete pathological response (meaning no cancer cells were found in the removed tissue) after receiving treatment before surgery.
  • People who have previously received a KRAS inhibitor or any other cancer treatment not specified in the trial's plan.
  • People who have previously had radiation therapy for their lung cancer, except for limited radiation used to manage symptoms before surgery.
  • People who experienced a severe immune-related side effect (Grade 3 or higher) during prior immunotherapy that has since resolved, or a moderate immune-related side effect (Grade 2 or higher) that has not yet resolved.
  • People with a currently active autoimmune disease, a history of autoimmune disease, or a condition that weakens the immune system.
  • People with serious heart or blood vessel disease.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026

Contact this trial

Principal Investigator: Clinical Trials, Hoffmann-La Roche

Phone: 888-662-6728 (U.S. only)

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
1 September 2026
Est. completion
31 January 2032

Primary endpoints

Disease-free Survival (DFS), as Determined by the Investigator

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov