Phase 2 Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Part A:
- Adults whose average seated blood pressure reading (the top number) is between 130 and 170 mmHg when measured in a clinic
- People who are either not taking any blood pressure medication, or who have been on a steady dose of up to 2 blood pressure medications
Part B:
- Adults whose average seated blood pressure reading (the top number) is between 140 and 170 mmHg when measured in a clinic
- People who have stopped all blood pressure medications — except possibly a calcium channel blocker or a water tablet (diuretic) — for at least 3 weeks before joining
Who may not be able to join:
- People whose high blood pressure is caused by another known medical condition, or who have high potassium levels in their blood (above 5 mmol/L)
- People whose kidneys are not working well enough, based on a specific kidney function measurement falling below a certain level (confirm with trial site)
Additional note: There are other eligibility requirements beyond those listed here that the trial site will assess.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Medical Director, Alnylam Pharmaceuticals
Phone: 1-877-ALNYLAM
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Part A: Percentage recovery from baseline in serum AGT; Part B: Percentage recovery from baseline in mean seated office SBP
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.