Phase 3 Myeloma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with B-cell chronic lymphocytic leukemia (a type of blood cancer) at an intermediate or high stage, based on specific medical criteria
• You have been diagnosed with multiple myeloma (a bone marrow cancer) at stage II or III, based on specific medical criteria
• You have been diagnosed with a B-cell non-Hodgkin lymphoma (another type of blood/lymph node cancer) at stage III or higher, including cases that have come back or stopped responding to treatment
• You have low levels of a key immune protein called IgG (below 5g/L) as measured at your screening appointment

Who may not be able to join:

• You received a stem cell transplant from a donor within the last 6 months
• You are currently receiving, or have received in the last 6 months, antibody/immunoglobulin replacement therapy (a treatment that boosts your immune proteins)
• You currently have an active infection of any kind
• You have another active cancer in addition to the one being studied
• You have a condition called primary immunodeficiency (a specific inherited immune system disorder)
• Your doctors estimate you have less than 1.5 years to live
• You have another serious ongoing illness that the trial doctor believes could interfere with the study or put you at extra risk
• You have previously had a serious allergic reaction to immunoglobulin treatments, blood, or any blood-based products
• You have a specific condition called Selective IgA Deficiency (confirm with trial site)
• You are pregnant, breastfeeding, have tested positive for pregnancy at screening, or are unwilling to use a reliable form of contraception throughout the study (a list of acceptable methods is defined by the trial)
• You have severe kidney disease, specifically a kidney function score below a certain level as measured by a blood test (confirm with trial site)
• Your liver enzyme levels (measured by a blood test at screening) are more than three times higher than the normal range
• You have a history of blood clots or related events — such as deep vein thrombosis, pulmonary embolism, stroke, heart attack, or certain other circulation problems — either once in the past year or twice in your lifetime
• You currently have a condition that causes your blood to be too thick or to clot too easily
• You currently have signs or symptoms of an active hepatitis B or hepatitis C infection
• You have uncontrolled high blood pressure (above specific levels) or a resting heart rate above 100 beats per minute
• You have had a known problem with substance or prescription drug misuse in the past 12 months
• You have taken part in another interventional clinical trial (one involving an experimental treatment unrelated to your current cancer) within the last 30 days
• You or your caregiver are unwilling or unlikely to follow the study rules and procedures throughout the trial

Important: Always verify eligibility with the trial site directly before applying.