Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have given their informed consent before the study begins
• People aged 18 to 75 years old (inclusive), of any gender
• People who have been diagnosed with locally advanced, unresectable (cannot be removed by surgery), recurrent, or metastatic pancreatic cancer confirmed by laboratory tissue or cell testing
• People who have already received at least one previous treatment for their cancer
• People who have at least one measurable area of cancer that can be tracked using standard imaging guidelines
• People with a performance status score of 0 or 1 on the ECOG scale, meaning they are fully active or restricted in physically strenuous activity but able to carry out light work (confirm with trial site)
• People with an expected survival of more than 3 months
• People who are able to swallow medications and follow the trial schedule and check-up visits
• People with adequate bone marrow and organ function within 7 days before the first dose, without having received blood products or cell growth factor treatments in the 14 days before starting treatment
• Women who could become pregnant must agree to abstain from heterosexual intercourse or use a highly effective form of contraception from the time of consent until 30 days after the last dose, have a negative blood pregnancy test within 7 days before starting treatment, and not be breastfeeding
• Male participants whose partners could become pregnant must agree to abstain from sex or use a highly effective form of contraception from the time of consent until 30 days after the last dose, and agree not to donate sperm during that period

Who may not be able to join:

• People with untreated or currently active cancer spread to the brain or central nervous system, or a history of cancer spreading to the membranes around the brain or spinal cord, the brainstem, or spinal cord compression
• People who have previously received general anaesthesia (confirm with trial site)
• People with a history of heart attack or unstable chest pain (unstable angina)
• People with a heart rhythm problem called atrioventricular block, or heart failure
• People with a history of stroke or mini-stroke (transient ischemic attack)
• People whose blood pressure is not well controlled even with medication
• People with abnormal blood clotting function
• People with a history of mental illness, cognitive impairment, or epilepsy
• People with a history of, or likelihood of, a difficult airway (confirm with trial site)
• People with a history of substance or drug abuse
• People who used certain medications that act on adrenaline receptors before joining the trial (confirm with trial site)
• People with abnormal laboratory test results (confirm with trial site for specific values)
• People with thyroid problems
• People who are allergic to any ingredient in the trial drug
• Women who are pregnant or breastfeeding
• People who have not used adequate birth control during the required period
• People who have recently taken part in another clinical drug trial or received an experimental treatment
• People whom the investigators consider unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.