Peripheral Neuropathy Trial, Recruiting NCT07599306 Sponsor: Fondazione Don Carlo Gnocchi ETS Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT07599306
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between the ages of 30 and 75 years
  • People who have previously been admitted to an intensive care unit (ICU) for at least 48 hours
  • People who have been assessed and found to have Post-Intensive Care Syndrome (PICS), meaning at least one of the following problems has been identified through objective testing at the start of the trial:
    • A nerve or muscle condition related to critical illness (such as Critical Illness Myopathy or Critical Illness Polyneuropathy), confirmed by a specific nerve and muscle test called an EMG
    • A thinking or memory difficulty, identified by a standard cognitive test (MoCA score below 26)
    • Signs of depression or psychological distress, identified by a standard questionnaire (PHQ-9 score of 10 or higher)
    • Malnutrition, identified using specific international criteria that look at weight loss, low body weight, reduced muscle mass, and reduced food intake or illness-related factors — and/or low muscle mass and reduced grip strength measured by specific physical tests
    • A disorder affecting bone health, identified by bone metabolism marker blood tests showing results outside the normal range
  • People who are able to read and sign a written consent form agreeing to take part

Who may not be able to join:

  • People with a particularly severe form of malnutrition, identified by a nutrition screening tool (CONUT score of 5 or higher)
  • People who are experiencing delirium (a state of acute confusion) at the time of enrolment, confirmed by a standard assessment tool (CAM or CAM-ICU)
  • People who had a documented diagnosis of severe cognitive impairment or dementia recorded in their medical notes before their ICU admission
  • People with any health condition — such as a serious bone, nerve, or physical disability — that is not related to PICS and would prevent full participation in the rehabilitation program (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 02-40308570

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fondazione Don Carlo Gnocchi ETS
Registry
ClinicalTrials.gov
Start date
13 April 2026
Est. completion
31 October 2028

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

The Cumulative incidence of all-cause mortality and all-cause rehospitalization

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov