Colorectal Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 18 years of age or older
- People whose general health and ability to carry out daily activities meets a certain minimum level, as assessed using a standard medical scale (confirm with trial site)
- People who have been diagnosed with a specific type of rectal cancer called rectal adenocarcinoma, confirmed through tissue testing
- People whose rectal cancer is at an early-to-moderate stage, based on MRI scan results, meaning it has not spread extensively to nearby lymph nodes or distant parts of the body (confirm with trial site)
- People whose treatment plan includes a curative approach aimed at preserving the rectum rather than removing it
- People whose case has been reviewed by a team of specialist doctors working together (a multidisciplinary tumor board)
- People who are able to provide written consent to participate in the trial
Who may not be able to join:
- People who have previously had radiotherapy to the pelvic area
- People who have had another cancer diagnosis, either currently or within the past 3 years, with an exception for certain treated skin cancers (basal cell carcinoma)
- People for whom chemotherapy, radiotherapy, or surgery would not be medically appropriate
- People whose MRI scan shows certain specific features, including affected lymph nodes outside the main rectal area, a higher number of involved lymph nodes, cancer growing into nearby blood vessels, or cancer reaching the surrounding tissue boundary
- People whose MRI scan shows the tumor has a mucus-producing (mucinous) appearance
- People who have already had a local surgical removal of the rectal tumor before joining the trial
- People who have a genetic enzyme deficiency that affects how the body processes certain chemotherapy drugs (DPD deficiency)
- People who, in the judgment of their treating doctor, are unable to understand what the study involves or to provide written informed consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
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Trial details
Where this trial is recruiting
Primary endpoints
Organ preservation
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Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.