Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with idiopathic Parkinson's disease (Parkinson's disease with no known external cause)
- People whose Parkinson's symptoms, when measured while not on medication, fall within a specific range of severity on a standard scale called Hoehn & Yahr (stage 2.5 to 4)
- People who have never had deep brain stimulation (DBS) surgery and whose doctors consider them suitable for a specific type of DBS surgery targeting one of two areas of the brain (STN or GPi) on both sides
- Alternatively, people who have previously had DBS surgery in both sides of the brain (STN or GPi) with a single implanted device, whose current DBS therapy is working well according to the investigator, and who agree to have their device replaced with the study device (G1010R)
- People who are willing and physically and mentally able to attend all required study visits and complete all study procedures
- People who are able to understand the study and sign a written consent form
Who may not be able to join:
- People who have medical reasons that make DBS surgery unsafe or unsuitable for them
- People who score above 25 on a standard depression questionnaire called the Beck Depression Inventory-II, indicating significant depression
- People who score below 24 on a standard memory and thinking test called the Mini-Mental State Examination (adjusted based on education level)
- People who have other serious health conditions that the investigator believes could interfere with DBS treatment
- People who already have another active medical implant in their body (other than DBS) or metal implants in their skull
- People who need to undergo certain medical treatments during the study period, including diathermy (a heat-based therapy), transcranial magnetic stimulation (TMS), or electroconvulsive therapy (ECT)
- People who have previously had brain surgery to destroy tissue (ablative neurosurgery) or stem cell therapy for Parkinson's disease
- People who are unable to complete at least three days in a row of detailed motor and sleep diaries
- People who are unable to follow their prescribed medication schedule or meet other study requirements
- People who are currently pregnant, breastfeeding, or planning to become pregnant during the study
- People who have any other condition that the investigators consider would make participation unsuitable
- People who have taken part in another interventional clinical trial within the four weeks before signing consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +86 010-60736388
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Proportion of aDBS Subjects With "On" Time Without Troublesome Dyskinesia Exceeding the Threshold
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.