Early Phase 1 Crohn's Disease and Colitis Trial, By Invitation
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 years or older.
- People who have been diagnosed with inflammatory bowel disease (IBD), which includes Crohn's disease or ulcerative colitis.
- People whose IBD is currently in remission, meaning their disease is not actively flaring, as confirmed by a doctor.
- People who are able to give their formal agreement to take part in the study.
- People who are able to follow the study procedures and use the stimulation device every day.
- People who have no medical reasons preventing them from having an MRI scan.
- People who have no medical reasons preventing them from using a non-invasive nerve stimulation device applied to the vagus nerve.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who are currently experiencing an active IBD flare or significant gut symptoms.
- People who have a serious or life-threatening medical condition alongside their IBD, such as active cancer.
- People who cannot have an MRI scan — for example, due to metal implants, a pacemaker, or severe claustrophobia.
- People who cannot use the nerve stimulation device — for example, due to serious heart rhythm problems, a very slow heart rate, an implanted electronic medical device, a recent history of trigeminal neuralgia, or a previous surgery to cut the vagus nerve.
- People who are currently pregnant.
- People who have been diagnosed with a severe neurological or psychiatric condition.
- People whose current medication affecting the brain or nervous system is being changed or adjusted.
- People who are unable to follow the study procedures or complete the required assessments.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in resting-state functional brain connectivity following non-invasive vagus nerve stimulation; Change in structural brain imaging measures following non-invasive vagus nerve stimulation
Can't join this trial?
Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.