Phase 2 Myeloma Trial, Recruiting NCT07638683 Sponsor: Shanghai Zhongshan Hospital Condition: Myeloma
Back to Myeloma

Phase 2 Myeloma Trial, Recruiting

NCT07638683
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older, of any sex or gender
  • People who have been diagnosed with multiple myeloma based on internationally recognised diagnostic guidelines (IMWG criteria)
  • People who have also been diagnosed with a condition called AL amyloidosis, confirmed through specific laboratory tests on tissue samples (including a Congo red stain test and at least one additional test such as immunohistochemistry, mass spectrometry, or electron microscopy)
  • People who have a detectable level of disease that can be measured at the start of the trial
  • People who have been newly diagnosed and have not yet received any treatment targeting plasma cells
  • People whose blood and organ function test results meet specific minimum levels — including blood cell counts, liver function, kidney function, and calcium levels (confirm with trial site for exact values)
  • People who are able and willing to use at least two effective methods of contraception throughout the study, if there is any possibility of pregnancy
  • People who are willing to sign a consent form confirming they understand and agree to participate

Who may not be able to join:

  • People who have previously received any treatment for myeloma or who have had a stem cell transplant
  • People who have a related but different blood or protein disorder, such as MGUS, smouldering myeloma, AL amyloidosis without myeloma, Waldenström macroglobulinemia, plasma cell leukaemia, POEMS syndrome, or another cancer diagnosed within the past three years
  • People who currently have an active infection or an autoimmune disease
  • People with diabetes, high blood pressure, or other ongoing health conditions that are not well controlled
  • People who are currently pregnant or breastfeeding
  • People who are already taking part in another clinical intervention study
  • People whom the trial doctor considers unsuitable for participation for any other reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Peng Liu, Fudan University

Phone: +86-021-64041990

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
22 May 2026
Est. completion
30 July 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

1-Year Progression-Free Survival (PFS) Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov