Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT07639242 Sponsor: UNC Lineberger Comprehensive Cancer Center Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT07639242
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are willing to give written consent to participate and agree to have their personal health information shared as required by the study.
  • People who are 18 years of age or older at the time of giving consent.
  • People whose general health and ability to carry out daily activities falls within a certain range, as measured by a standard oncology scale called the ECOG scale (scores 0–2, meaning fully active to limited in strenuous activity but able to care for oneself).
  • People who have been diagnosed with Stage IIIB, IIIC, or Stage IV Non-Small Cell Lung Cancer (a type of lung cancer) that has not been treated before and cannot be treated with the aim of curing it.
  • People whose cancer can be measured on scans according to standard criteria (called RECIST v1.1), with those measurements taken within 28 days before starting treatment.
  • People whose cancer has a specific genetic change called a KRAS G12C mutation, confirmed by laboratory testing of tumour tissue or a blood-based test, carried out in a certified laboratory.
  • People whose cancer has been tested and shows a PD-L1 score (a marker measured on tumour cells) of between 1% and 49%, confirmed by a certified laboratory.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have a serious existing medical condition that the investigating doctor believes would make participation unsafe, including conditions such as interstitial lung disease (scarring or inflammation in the lungs), severe difficulty breathing at rest, or uncontrolled fluid build-up around the heart or lungs.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 July 2026

Contact this trial

Principal Investigator: Shetal A Patel, MD, PhD, UNC Lineberger Comprehensive Cancer Center

Phone: 919-984-0000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
UNC Lineberger Comprehensive Cancer Center
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
21 June 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Progression free survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov