Rare disease
Polycythaemia Vera
Clinical trials recruiting in Australia for Polycythaemia Vera, a rare disease, as the public registries list them.
Also called: Acquired primary erythrocytosis; Osler-Vaquez disease; PV; Polycythemia rubra vera; Vaquez disease; Polycythemia vera; Polycythaemia rubra vera; PRV; Primary polycythaemia; Primary polycythemia
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At a glance
6 trials recruiting in Australia
57 trials recruiting overseas
1-5 / 10 000 (Point prevalence, Europe, Validated) prevalence
All ages age of onset
15 October 2026 date last checked
Trials in Australia
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Phase 2
Phase 2 study for people with Polycythaemia Vera
Where- Linear Clinical Research, Nedlands (WA) — Recruiting
- Western Health, Saint Albans (VIC) — Recruiting
- St. Vincent's Hospital, Sydney (NSW) — Recruiting
- Perth Blood Institute, West Perth (WA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Disc Medicine, IncTimelineStarted 6 June 2022 Today 16 October 2026 Estimated completion 1 May 2027NCT05320198 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Polycythaemia Vera
Where- Royal Prince Alfred Hospital ( Site 1003), Camperdown (NSW) — Recruiting
- Royal North Shore Hospital ( Site 1001), St Leonards (NSW) — Recruiting
- Sunshine Coast Hematology and Oncology Clinic ( Site 1006), Buderim (QLD) — Recruiting
- Gold Coast University Hospital-Cancer and Blood Disorders Clinical Trial Team ( Site 1002), Southport (QLD) — Recruiting
- Royal Adelaide Hospital-Haematology Clinical Trials Unit ( Site 1000), Adelaide (SA) — Recruiting
- Monash Health ( Site 1004), Clayton (VIC) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Merck Sharp & Dohme LLCTimelineStarted 23 May 2024 Today 16 October 2026 Estimated completion 4 December 2034NCT06351631 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Polycythaemia Vera
Where- Novartis Investigative Site, Adelaide (SA) — Recruiting
- Novartis Investigative Site, Clayton (VIC) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Novartis PharmaceuticalsTimelineStarted 27 May 2026 Today 16 October 2026 Estimated completion 17 May 2028NCT07357727 · Checked 15 October 2026
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Recruiting Phase 3
Phase 3 study for people with Polycythaemia Vera
Where- Perth Blood Institute, West Perth (WA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Ono Pharmaceutical Co., Ltd.TimelineStarted 25 May 2026 Today 16 October 2026 Estimated completion 1 September 2028NCT07429266 · Checked 12 October 2026
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Recruiting Phase 1
Phase 1 study for people with Polycythaemia Vera
Where- Concord General Repatriation Hospital, Concord (NSW) — Recruiting
- Royal North Shore Hospital, St Leonards (NSW) — Recruiting
- Icon Cancer Centre, Auchenflower (QLD) — Recruiting
- Epworth Health Care, East Melbourne (VIC) — Recruiting
- Linear Clinical Research, Nedlands (WA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Incyte CorporationTimelineStarted 11 May 2026 Today 16 October 2026 Estimated completion 24 May 2030NCT07441694 · Checked 15 October 2026
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Recruiting Phase 1
Phase 1 study for people with Polycythaemia Vera
Where- Royal Adelaide Hospital, Adelaide (SA) — Recruiting
- Monash Health, Monash Medical Centre, Clayton (VIC) — Recruiting
- One Clinical Research, Nedlands (WA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Prelude Therapeutics IncorporatedTimelineStarted 29 April 2026 Today 16 October 2026 Estimated completion 1 April 2028NCT07469891 · Checked 11 October 2026
Trials overseas
57 trials for this disease are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
Trials not shown here
Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Key facts
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com).
About Polycythaemia Vera
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
Polycythemia vera is a condition characterized by an increased number of red blood cells in the bloodstream. Affected individuals may also have excess white blood cells and blood clotting cells called platelets. These extra cells and platelets cause the blood to be thicker than normal. As a result, abnormal blood clots are more likely to form and block the flow of blood through arteries and veins. Individuals with polycythemia vera have an increased risk of deep vein thrombosis (DVT), a type of blood clot that occurs in the deep veins of the arms or legs. If a DVT travels through the bloodstream and lodges in the lungs, it can cause a life-threatening clot known as a pulmonary embolism (PE). Affected individuals also have an increased risk of heart attack and stroke caused by blood clots in the heart and brain. Polycythemia vera typically develops in adulthood, around age 60, although in rare cases it occurs in children and young adults. This condition may not cause any symptoms in its early stages. Some people with polycythemia vera experience headaches, dizziness, ringing in the ears (tinnitus), impaired vision, or itchy skin. Affected individuals frequently have reddened skin because of the extra red blood cells. Other complications of polycythemia vera include an enlarged spleen (splenomegaly), stomach ulcers, gout (a form of arthritis caused by a buildup of uric acid in the joints), heart disease, and cancer of blood-forming cells (leukemia).
US source; availability in Australia may differ.
Source: MedlinePlus Genetics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- Orphanet / Orphadata – prevalence, age of onset, inheritance, genes and alternative names, used under CC BY 4.0
- ClinicalTrials.gov processing date: 15 October 2026.
- This page last checked by Voxsanity: 15 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Orphanet citation
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com). Accessed 20 September 2026.
Polycythaemia Vera is one of the rare diseases tracked on the Voxsanity rare disease hub, where you can compare it with every other rare condition we follow and filter trials by country.
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